Table 1.
Clinical parameters of the two groups enrolled in the study
| Parameters | Cases (n = 40) CeD patients |
Controls (n = 40) Healthy volunteers |
Statistical value | P value |
|---|---|---|---|---|
| Min–max age | 19–65 | 19–66 | ||
| Mean age ± SD | 44 ± 12.0 | 42.6 ± 11.9 | t = 0.513 | 0.994 |
| Sex F/M (%F) | 29F/11 M (72.5%) | 29F/11 M (72.5%) | – | – |
| BMI | 20.16 ± 4.3 | 20.33 ± 3.93 | t = − 0.185 | 0.691 |
| Nationality (%) | – | – | ||
| Han | 6/40 (15%) | 6/40 (15%) | ||
| Kazakh | 15/40 (37.5%) | 15/40 (37.5%) | ||
| Uygur | 19/40 (47.5%) | 19/40 (47.5%) | ||
| Disease comorbidities (%) | ||||
| Thyroid diseases | 12/40 (30%) | 4/40 (7.5%) | χ2 = 5.000 | 0.025 |
| Osteoporosis | 12/40 (30%) | 4/40 (10%) | χ2 = 5.000 | 0.025 |
| Anemic | 14/40 (35%) | 2/40 (5%) | χ2 = 11.250 | 0.001 |
| Vitamin D deficiency | 17/40 (42.5%) | 7/40 (22.5%) | χ2 = 5.952 | 0.015 |
| Anxiety and depression | 2/40 (5%) | 0/40 (0%) | χ2 = 2.051 | 0.152 |
| Mean tTG-IgA (% +) |
2596.2 40/40 (+) (100%) |
0/40 (−) (0%) | ||
|
Duodenal biopsy (Marsh index) (%) |
5/40 M3a (12.5%) 16/40 M3b (12.5%) 19/40 M3c (47.5%) |
40/40 M0 (100%) | ||
|
Clinical symptoms (%) (Classical/non-classical) |
18/40 Cla (45%) 22/40 N-Cla (55%) |
– |
CeD celiac disease, BMI body mass index, F female, M male, tTG -IgA anti tissue-transglutaminase 2 IgA, Marsh Index M3a: Marsh 3A, M3b: Marsh 3B, M3c: Marsh 3C