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. 2025 Aug 29;13:e19970. doi: 10.7717/peerj.19970

Table 2. Comparison of several variables in patients and controls.

Variable Group Total
Mean ± SD
p
Control (n = 40)
Mean ± SD
Patient (n = 39)
Mean ± SD
Age, years 66 ± 11.6 66.9 ± 11 66.5 ± 11.3 0.690
Female, n (%) 17 (42.5) 17 (43.6) 34 (43) 0.922
Pulse beats/ minute 81.8 ± 8.5 86.1 ± 14.9 83.9 ± 12.2 0.038
Hemoglobin (g/dl) 13.2 ± 1.4 12.7 ± 2.5 12.9 ± 2.0 0.004
Sodium, mmol/L 138.1 ± 2.9 136.2 ± 3.4 137.2 ± 3.3 0.764
Chlor, mmol/L 104.8 ± 12.0 130.2 ± 7.5 104.0 ± 9.9 0.689
Calcium, mmol/L 9.4 ± 0.6 8.9 ± 0.8 9.2 ± 0.7 0.152
Control (n = 40)
Median (IQR)
Patient (n = 39)
Median (IQR)
Total
Median (IQR)
p
Fever, °C 36.5 (36.4–36.7) 36.1 (36.0–36.5) 36.4 (36.0–36.6) <0.001
Systolic BP, mm Hg 120.5 (115.3–125.0) 130.0 (123.0–136.0) 124.0 (117.0–130.0) <0.001
Diastolic BP, mm Hg 69.0 (64.0–74.8) 77.0 (70.0–80.0) 74.0 (67.0–78.0) <0.001
Respiration rate 16.0 (15.0–17.8) 18.0 (17.0–22.0) 17.0 (15.0–19.0) <0.001
Glucose, mg/dl 128.0 (109.0–144.3) 125.0 (104.0–195.0) 128.0 (106.0–152.0) 0.521
WBC, ×10 3 /μL 8.5 (7.4–9.5) 12.1 (8.5–17.9) 9.1 (7.7–12.7) <0.001
Platelet, ×10 3 /μL 306.0 (254.5–324.5) 267.0 (225.0–344.0) 298.0 (236.0–326.0) 0.450
AST, U/L 26.6 (24.6–29.9) 23.2 (18.9–35.0) 26.1 (22.1–31.5) 0.052
ALT, U/L 26.5 (23.4–34.1) 15.0 (11.0–23.0) 23.4 (15.0–32.5) <0.001
BUN, mg / dL 17.0 (13.4–20.4) 18.8 (15.4–22.4) 18.4 (14.3–21.5) 0.384
Creatine, mg/dL 0.84 (0.65–1.17) 0.89 (0.80–1.13) 0.86 (0.74–1.13) 0.152
Potassium, mmol/L 4.2 (3.9–4.6) 4.3 (3.9–4.7) 4.2 (3.9–4.6) 0.600
Ep300, ng/ml 366.5 (281.1–423.8) 390.9 (332.9–455.9) 374.4 (327.8–432.0) 0.379
FOXO4, ng/ml 1.11 (0.81–1.39) 1.30 (1.12–1.68) 1.21 (0.99–1.49) 0.004