Table 2.
Quality of studies with respect to how reliable they are in assessing accuracy (3-5 indicates low quality, 6-7 indicates moderate quality, and 8-9 indicates high quality).
| System number | Name of the gamified interactive system | Reference | Reference standard | Relevance of controls | Sample size | Quality of studies |
| Sys2 | Fun Cube | [52] | 1 | 2 | 3 | 6 |
| Sys3 | VAP-Sa | [54] | 3 | 2 | 2 | 7 |
| Sys4 | VREAD | [56] | 2 | 2 | 3 | 7 |
| Sys6 | SmartAging | [62] | 1 | 1 | 3 | 5 |
| Sys6 | SmartAging | [63] | 3 | 3 | 3 | 9 |
| Sys6 | SmartAging | [64] | 3 | 2 | 3 | 8 |
| Sys7 | FitForAll | [67] | 3 | 3 | 3 | 9 |
| Sys9 | Find the pair | [69] | 3 | 1 | 3 | 7 |
| Sys10 | VAP-Mb | [70] | 3 | 2 | 3 | 8 |
| Sys13 | Smartkuber | [75] | 1 | 1 | 1 | 3 |
| Sys14 | —c | [77] | 1 | 1 | 3 | 5 |
| Sys16 | — | [79] | 1 | 2 | 3 | 6 |
| Sys17 | Dr. Solitaire | [82] | 3 | 2 | 3 | 8 |
| Sys17 | Dr. Solitaire | [83] | 3 | 2 | 3 | 8 |
| Sys20 | Panoramix | [88] | 2 | 2 | 1 | 5 |
| Sys20 | Panoramix | [89] | 2 | 3 | 2 | 7 |
| Sys20 | Panoramix | [90] | 2 | 3 | 3 | 8 |
| Sys20 | Panoramix | [91] | 2 | 3 | 3 | 8 |
| Sys20 | Panoramix | [92] | 3 | 3 | 2 | 8 |
| Sys21 | Neuro-World | [93] | 1 | 1 | 2 | 4 |
| Sys21 | Neuro-World | [94] | 1 | 1 | 2 | 4 |
| Sys25 | RE@CH | [98] | 1 | 2 | 3 | 6 |
| Sys28 | Holey Moley | [101] | 1 | 1 | 3 | 5 |
| Sys29 | Hit-the-ball | [102] | 1 | 3 | 3 | 7 |
| Sys30 | Virtual Supermarket | [104] | 3 | 2 | 3 | 8 |
| Sys30 | Virtual Supermarket | [105] | 3 | 2 | 3 | 8 |
| Sys30 | Virtual Supermarket | [106] | 3 | 3 | 3 | 9 |
| Sys33 | Lucy | [109] | 3 | 2 | 3 | 8 |
| Sys36 | COGNIPLAT | [113] | 1 | 2 | 1 | 4 |
| Sys36 | COGNIPLAT | [114] | 1 | 2 | 1 | 4 |
| Sys48 | The Ryokansan | [127] | 3 | 3 | 3 | 9 |
aAUC: area under the curve.
bVAP-S: virtual action planning supermarket.
cNot available.
dHRMG: high-resolution monitoring games.
eMoCA: Montreal Cognitive Assessment.
fMMSE: Mini-Mental State Examination.
gEEG: electroencephalogram.