TABLE 2.
Comparison of refractive and ocular biometric components (mean ± standard deviation) at the initial and final visits between the two groups.
| Infantile group, N = 34, OD |
Infantile group, N = 34, OS |
Late-onset group, N = 63, OD |
Late-onset group, N = 63, OS |
p-Value (initial vs. final) | p-Value (groups) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Initial | Final | Initial | Final | Initial | Final | Initial | Final | |||
| Refractive errors | ||||||||||
| SER(D) | 3.76 ± 2.07 | 2.73 ± 2.56 | 3.95 ± 2.07 | 3.06 ± 2.38 | 4.89 ± 1.85 | 4.37 ± 1.85 | 4.84 ± 2.17 | 4.30 ± 2.01 | p = 0.001* | p < 0.001* |
| J0(D) | 0.28 ± 0.36 | 0.25 ± 0.48 | 0.29 ± 0.44 | 0.37 ± 0.64 | 0.34 ± 0.43 | 0.41 ± 0.58 | 0.32 ± 0.43 | 0.41 ± 0.50 | p = 0.22 | p = 0.16 |
| J45(D) | −0.04 ± 0.22 | −0.03 ± 0.18 | 0.03 ± 0.28 | 0.01 ± 0.35 | 0.05 ± 0.33 | 0.06 ± 0.40 | 0.01 ± 0.29 | −0.02 ± 0.34 | p = 0.82 | p = 0.25 |
| Measured biometric parameters | ||||||||||
| Axial length (mm) | 21.50 ± 0.98 | 22.44 ± 0.97 | 21.36 ± 0.94 | 22.26 ± 0.97 | 21.20 ± 0.96 | 21.86 ± 1.05 | 21.19 ± 1.06 | 21.91 ± 1.09 | p < 0.001* | p = 0.001* |
| Anterior chamber depth (mm) | 3.31 ± 0.32 | 3.61 ± 0.26 | 3.40 ± 0.28 | 3.57 ± 0.28 | 3.23 ± 0.28 | 3.48 ± 0.26 | 3.19 ± 0.40 | 3.50 ± 0.28 | p < 0.001* | p = 0.003* |
| Lens thickness (mm) | 3.72 ± 0.29 | 3.47 ± 0.22 | 3.72 ± 0.28 | 3.48 ± 0.19 | 3.72 ± 0.34 | 3.52 ± 0.25 | 3.81 ± 0.48 | 3.59 ± 0.33 | p < 0.001* | p = 0.02* |
| Central cornea thickness (μm) | 554.00 ± 37.52 | 559.91 ± 32.89 | 553.55 ± 36.13 | 560.81 ± 31.55 | 559.81 ± 35.82 | 562.56 ± 37.38 | 558.66 ± 36.57 | 564.84 ± 36.48 | p = 0.16 | p = 0.21 |
| Least corneal Power (D) | 42.82 ± 1.49 | 42.59 ± 1.52 | 42.88 ± 1.67 | 42.55 ± 1.53 | 42.25 ± 1.63 | 42.05 ± 1.60 | 42.35 ± 1.68 | 42.19 ± 1.62 | p = 0.20 | p = 0.005* |
| Greatest corneal power (D) | 44.08 ± 1.60 | 44.03 ± 1.42 | 44.37 ± 1.64 | 44.24 ± 1.50 | 44.00 ± 1.68 | 43.84 ± 1.64 | 43.95 ± 1.60 | 43.88 ± 1.61 | p = 0.54 | p = 0.13 |
| Calculated biometric parameters | ||||||||||
| Mean corneal power (D) | 43.45 ± 1.47 | 43.31 ± 1.39 | 43.62 ± 1.53 | 43.39 ± 1.41 | 43.13 ± 1.59 | 42.94 ± 1.52 | 43. 51 ± 1.57 | 43.04 ± 1.52 | p = 0.31 | p = 0.02* |
| AL/CR ratio | 2.76 ± 0.11 | 2.88 ± 0.12 | 2.75 ± 0.11 | 2.86 ± 0.11 | 2.70 ± 0.10 | 2.78 ± 0.12 | 2.70 ± 0.11 | 2.79 ± 0.12 | p < 0.001* | p < 0.001* |
Note: Generalised Estimating Equations (GEE) analysis was used to compare the two groups and initial and final visits after adjusting with sex; data from both eyes were included.
Abbreviations: AL/CR, axial length to corneal radius ratio; OD, right eye; OS, left eye; SER, spherical equivalent refraction.
*
indicates statistically significant difference.