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. 2025 Jul 31;2025:3520935. doi: 10.1155/bmri/3520935

Table 2.

Stability of vancomycin in intracellular and extracellular fluids (n = 5).

Treatment Concentration (mg/mL) Intracellular fluid Extracellular fluid
Founded (mg/mL) RSD (%) Founded (mg/mL) RSD (%)
Storage at −40°C for 3 days 0.01 0.0113 ± 0.0003 2.55 0.0103 ± 0.0006 6.13
1 1.12 ± 0.03 2.57 1.04 ± 0.02 1.79
6.4 6.83 ± 0.10 1.50 6.64 ± 0.34 5.18

Three freeze-thaw cycles 0.01 0.0109 ± 0.0009 8.13 0.0105 ± 0.0010 9.36
1 0.90 ± 0.02 2.20 0.94 ± 0.03 2.83
6.4 6.35 ± 0.24 3.75 6.88 ± 0.07 1.02

Immediately determine 0.01 0.0105 ± 0.0004 3.75 0.0105 ± 0.0007 6.42
1 1.05 ± 0.01 1.04 1.12 ± 0.03 2.80
6.4 6.51 ± 0.54 8.23 6.37 ± 0.05 0.78

Abbreviation: RSD, relative standard deviation.