Table 1.
KRT18 expression correlates with clinicopathological features (chi-square test)
| Characteristics | Low expression of KRT18 | High expression of KRT18 | P value |
|---|---|---|---|
| n | 269 | 270 | |
| Pathologic T-stage, n (%) | 0.012 | ||
| T1 | 102 (19%) | 74 (13.8%) | |
| T2 | 140 (26.1%) | 152 (28.4%) | |
| T3 | 16 (3%) | 33 (6.2%) | |
| T4 | 9 (1.7%) | 10 (1.9%) | |
| Pathologic N-stage, n (%) | 0.018 | ||
| N0 | 181 (34.6%) | 169 (32.3%) | |
| N1 | 49 (9.4%) | 48 (9.2%) | |
| N2 | 25 (4.8%) | 49 (9.4%) | |
| N3 | 2 (0.4%) | 0 (0%) | |
| Pathologic M stage, n (%) | 0.626 | ||
| M0 | 179 (45.9%) | 186 (47.7%) | |
| M1 | 11 (2.8%) | 14 (3.6%) | |
| Pathologic stage, n (%) | 0.027 | ||
| Stage I | 162 (30.5%) | 134 (25.2%) | |
| Stage II | 58 (10.9%) | 67 (12.6%) | |
| Stage III | 31 (5.8%) | 53 (10%) | |
| Stage IV | 12 (2.3%) | 14 (2.6%) | |
| Gender, n (%) | 0.180 | ||
| Female | 152 (28.2%) | 137 (25.4%) | |
| Male | 117 (21.7%) | 133 (24.7%) | |
| Age, n (%) | 0.725 | ||
| < = 65 | 126 (24.2%) | 131 (25.2%) | |
| > 65 | 133 (25.6%) | 130 (25%) | |
| Smoker, n (%) | 0.113 | ||
| No | 45 (8.6%) | 32 (6.1%) | |
| Yes | 218 (41.5%) | 230 (43.8%) | |
| Number pack years smoked, n (%) | 0.652 | ||
| < 40 | 87 (23.6%) | 101 (27.4%) | |
| > = 40 | 88 (23.8%) | 93 (25.2%) |
All content highlighted in bold in the tables indicates that the corresponding p-values meet the criterion of statistical significance (i.e., p<0.05).