Table 2.
Univariate and multivariate analyses of clinicopathological parameters in patients with LUAD
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |||
| Pathologic T-stage | 527 | |||||
| T1 | 176 | Reference | Reference | |||
| T2 | 285 | 1.507 (1.059– 2.146) | 0.023 | 1.534 (0.974– 2.415) | 0.065 | |
| T3&T4 | 66 | 3.095 (1.967– 4.868) | < 0.001 | 2.688 (1.466– 4.928) | 0.001 | |
| Pathologic N-stage | 514 | |||||
| N0 | 345 | Reference | Reference | |||
| N1 | 96 | 2.293 (1.632– 3.221) | < 0.001 | 1.987 (1.339– 2.949) | < 0.001 | |
| N2 | 71 | 3.133 (2.154– 4.559) | < 0.001 | 2.140 (1.012– 4.526) | 0.047 | |
| N3 | 2 | 0.000 (0.000– Inf) | 0.994 | 0.000 (0.000– Inf) | 0.993 | |
| Pathologic M stage | 381 | |||||
| M0 | 356 | Reference | Reference | |||
| M1 | 25 | 2.176 (1.272–3.722) | 0.005 | 1.196 (0.557–2.565) | 0.646 | |
| Pathologic stage | 522 | |||||
| Stage I&Stage II | 415 | Reference | Reference | |||
| Stage III&Stage IV | 107 | 2.710 (1.994–3.685) | < 0.001 | 1.460 (0.679–3.139) | 0.333 | |
| Gender | 530 | |||||
| Female | 283 | Reference | ||||
| Male | 247 | 1.087 (0.816–1.448) | 0.569 | |||
| Age | 520 | |||||
| < = 65 | 257 | Reference | ||||
| > 65 | 263 | 1.216 (0.910–1.625) | 0.186 | |||
| Number pack years smoked | 363 | |||||
| < 40 | 183 | Reference | ||||
| > = 40 | 180 | 1.073 (0.753–1.528) | 0.697 | |||
All content highlighted in bold in the tables indicates that the corresponding p-values meet the criterion of statistical significance (i.e., p<0.05).