. 2025 Aug 19;12:1612779. doi: 10.3389/fmed.2025.1612779

Table 3.

Secondary outcomes.

Recovery quality parameter	Placebo n = 70	Remimazolam (2.5 mg) n = 71	Remimazolam (5.0 mg) n = 71	p Value
Total dosage of remimazolam, mg	–	5.00 (3.75–7.50)	7.50 (5.00–10.00)^b	<0.001
Total dosage of rescue propofol, mg	30.50 (0.00–42.13)	0.00 (0.00–0.00)^a	0.00 (0.00–0.00)^a	<0.001
Duration of agitation, min	14 (11–19)	7 (4–10)^a	4 (2–7)^a	<0.001
Time to discharge from PACU from last dose of IMP/rescue, min	54 (47–59)	38 (34–43)^a	46 (42–49)^ab	<0.001

Data are presented as median (inter-quartile range) and comparisons among groups were performed using Kruskal-Wallis tests, followed by Bonferroni-adjusted pairwise comparisons. Compared with Group Placebo, ^ap < 0.05. Compared with Group Remimazolam (2.5 mg), ^bp < 0.05.

PACU, post-anesthesia care unit; IMP, investigational medicinal product.