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. 2025 Aug 19;16:1611867. doi: 10.3389/fimmu.2025.1611867

Table 3.

Subgroup analysis of the effect of the NHR on psoriasis (N = 21,723).

Subgroup N OR (95% CI) P for interaction
Age (year) 0.852
 20∼39 8,651 1.06 (0.97, 1.16)
 40∼59 7,982 1.03 (0.95, 1.11)
 ≥60 5,090 1.06 (0.96, 1.17)
Sex 0.884
 Male 10,467 1.04 (0.97, 1.12)
 Female 11,256 1.05 (0.98, 1.13)
Race 0.416
 Mexican American 3,502 0.96 (0.79, 1.16)
 Non-Hispanic White 1,770 1.07 (0.89, 1.29)
 Non-Hispanic Black 9,714 1.02 (0.96, 1.09)
 Other Hispanic 4,573 1.13 (0.99, 1.31)
 Other race/multiracial 2,164 1.15 (0.98, 1.35)
Education 0.396
 Under high school 5,257 0.98 (0.87, 1.09)
 High School or equivalent 4,927 1.07 (0.96, 1.18)
 Above high school 11,539 1.06 (0.99, 1.14)
Marital status 0.357
 Married/cohabiting 4,313 1.04 (0.91, 1.18)
 Widowed/divorced/separated 13,095 1.08 (1.01, 1.15)
 Never married 4,315 0.98 (0.88, 1.10)
BMI 0.903
 <25 6,520 1.02 (0.91, 1.16)
 25∼29.9 7,325 1.05 (0.96, 1.14)
 ≥30 7,878 1.06 (0.98, 1.14)
PIR 0.649
 <1.30 6,527 1.06 (0.98, 1.16)
 1.30∼3.49 8,790 1.06 (0.98, 1.15)
 ≥3.50 6,406 1.01 (0.91, 1.11)
Cigarette Use 0.625
 Smoked ≥ 100 cigarettes in life 9,689 1.04 (0.97, 1.10)
 Smoked < 100 cigarettes in life 12,034 1.06 (0.98, 1.15)
Diabetes 0.787
 Yes 2,699 1.03 (0.92, 1.16)
 No 19,024 1.05 (0.99, 1.11)
Hypertension 0.993
 Yes 6,951 1.05 (0.97, 1.13)
 No 14,772 1.05 (0.98, 1.12)
Cancer 0.760
 Yes 1,678 1.07 (0.94, 1.21)
 No 20,045 1.04 (0.99, 1.10)
Had at least 12 alcohol drinks one year 0.048
 Yes 16,359 1.02 (0.96, 1.08)
 No 5,364 1.14 (1.04, 1.26)
Heart attack 0.339
 Yes 732 0.96 (0.80, 1.16)
 No 20,991 1.06 (1.00, 1.11)

Age, sex, race, PIR, BMI, cigarette use, hypertension, education, diabetes, cancer, marital status, heart attack and alcohol use were adjusted.

BMI, body mass index; PIR, family income–poverty ratio; NHR, neutrophil-to-high-density lipoprotein cholesterol ratio.