FIG. 1.

(a) Deduced amino acid sequence of APN from S. litura. The 2,856-bp cDNA clone encodes a 952-amino-acid polypeptide. The putative NH₂-terminal cleavable peptide and the GPI signal peptide at the COOH terminus are double underlined. The zinc metallopeptidase signature is indicated with a dotted line. The putative N-glycosylation sites are underlined. The four Cys residues that are conserved among eukaryotic aminopeptidases are in boldface. (b) Schematic representation and putative signature domains of S. litura APN.