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. 2002 Sep;68(9):4448–4456. doi: 10.1128/AEM.68.9.4448-4456.2002

TABLE 3.

MCA of the effects of various parameters on flux (J) through the glycerol synthesis pathway

Metabolic control coefficienta Value at the following phase of growth:
Early exponentialb Mid-exponentialc Early stationaryd
Response     coefficients
    RNADHJ 0.03 0.05 0.08
    RDHAPJ 0.48 0.60 0.69
    RNADJ −0.02 −0.02 −0.03
    RF1,6BPJ −0.16 −0.11 −0.10
    RATPJ −0.42 −0.50 −0.21
    RADPJ −0.14 −0.10 −0.14
Flux control     coefficients
    Cv1J 0.85 0.88 0.83
    Cv2J 0.15 0.12 0.17
a

Metabolic control coefficients were calculated by the Gepasi simulated model of the glycerol synthesis pathway. v1, rate of Gpd p-catalyzed reaction; v2, rate of Gpp p-catalyzed reaction.

b

OD600, 0.4 [400 to 430 min].

c

OD600, 0.7 [600 to 630 min].

d

OD600, 1.1 [970 to 1,000 min].

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