Skip to main content
[Preprint]. 2025 Aug 26:rs.3.rs-7418040. [Version 1] doi: 10.21203/rs.3.rs-7418040/v1

Table 4.

Sex differences in associations of daily average negative mood and daily average ambulatory autonomic function as indexed by deceleration capacity of heart rate.

Women
N = 121
Men
N = 159
Percent difference (95% CI) in daily means of ln DC per 1-log-unit increase in daily mean negative mood score P for sex interaction *
Unadjusted −4.5 (−7.8, −1.2) 0.5 (−2.0, 2.9) 0.02
Adjusted for sociodemographic factors* −3.8 (−6.8, −0.9) 0.3 (−2.0, 2.5) 0.03
Adjusted for the above plus CAD risk factors −3.6 (−6.2, −1.1) 0.7 (−1.3, 2.6) 0.009
Adjusted for the above plus psychosocial scales and antidepressant medication use −3.5 (−6.2, −0.8) 0.9 (−1.2, 3.0) 0.007
Adjusted for the above plus CAD severity −4.3 (−7.3, −1.3) 0.8 (−1.5, 3.1) 0.005
Adjusted for the above plus cardiovascular medications −4.2 (−7.1, −1.2) 0.6 (−1.7, 3.0) 0.008

CI: confidence interval; DC: deceleration capacity; CAD: coronary artery disease.

*

Age, sex (in overall models), race (black versus non-black), married, education > 12 years.

Ever smoking, BMI, history of hypertension and diabetes mellitus.

Beck Depression Inventory score, and PTSD Symptom Checklist score at the clinic visit.

Left ventricular ejection fraction, Gensini CAD severity score, ST-segment elevation MI.

Beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and statins.