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. 2025 Aug 21;12:1647313. doi: 10.3389/fcvm.2025.1647313

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© 2025 Wang, Qiao, Song, Wang, Yang, Lin and Meng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Three ROC curves labeled A, B, and C show sensitivity versus 1-specificity. A: Overall group, AUC 0.773, optimal cut-off 1.75 mm. B: Under 60 years, AUC 0.777, cut-off 1.75 mm. C: Over 60 years, AUC 0.767, cut-off 1.95 mm. — Receiver Operating Characteristic (ROC) curve of patent foramen ovale (PFO) diameter for cryptogenic stroke prediction. (A) ROC curve of the overall group; (B) ROC curve of the subgroup aged < 60 years; (C) ROC curve of the subgroup aged ≥ 60 years.