Table 3A.
Multivariate logistic regression analysis of the influencing factors for cryptogenic stroke related to PFO in people aged < 60 years.
| Variables | CS vs. NS | CS vs. NCS | ||||||
|---|---|---|---|---|---|---|---|---|
| B | P value | OR | 95% CI | B | P value | OR | 95% CI | |
| PFO diameter | 0.755 | 0.120 | 2.129 | 0.821–5.517 | 0.464 | 0.329 | 1.591 | 0.626–4.040 |
| WBC | 0.339 | 0.185 | 1.403 | 0.851–2.316 | 0.207 | 0.373 | 1.229 | 0.780–1.937 |
| HbA1c | 1.597 | 0.102 | 4.938 | 0.729–33.46 | 1.019 | 0.282 | 2.770 | 0.443–17.71 |
| Diabetes | ||||||||
| No | 4.019 | 0.232 | 55.623 | 0.08–40,361 | 1.896 | 0.541 | 6.660 | 0.015–2,928 |
| Yes | 0.018 | 0.000–12.5 | 0.150 | 0.00–66.667 | ||||
| Previous Stroke/TIA | ||||||||
| No | −19.584 | 0.986 | –a | –a | −1.495 | 0.296 | 0.244 | 0.014–3.708 |
| Yes | 4.098 | 0.27–71.429 | ||||||
| Cortical infarct on imaging | ||||||||
| No | −16.436 | 0.982 | –a | –a | 0.471 | 0.790 | 1.601 | 0.050–51.07 |
| Yes | 0.625 | 0.020–20.00 | ||||||
| Small RLS | −0.723 | 0.566 | 0.485 | 0.041–5.753 | −2.028 | 0.099 | 0.132 | 0.012–1.463 |
| Large RLS | 2.062 | 0.174–24.39 | 7.576 | 0.684–83.33 | ||||
a
Odds ratio not calculable due to complete separation.
NS, no stroke; CS, cryptogenic stroke; NCS, non-cryptogenic stroke; TIA, transient ischemic attack; RLS, right-to-left shunt; PFO, patent foramen ovale; WBC, white blood cell count; HbA1c, glycated hemoglobin A1c.