Table 3B.
Multivariate logistic regression analysis of the influencing factors for cryptogenic stroke related to PFO in people aged ≥ 60 years.
| Variables | CS vs. NS | CS vs. NCS | ||||||
|---|---|---|---|---|---|---|---|---|
| B | P value | OR | 95% CI | B | P value | OR | 95% CI | |
| PFO diameter | 0.895 | 0.009 | 2.446 | 1.251–4.783 | 0.552 | 0.037 | 1.737 | 1.033–2.922 |
| WBC | 0.143 | 0.319 | 1.154 | 0.871–1.529 | 0.015 | 0.903 | 1.015 | 0.802–1.284 |
| HbA1c | 0.085 | 0.865 | 1.089 | 0.409–2.898 | 0.260 | 0.427 | 1.297 | 0.683–2.464 |
| Diabetes | ||||||||
| No | −1.202 | 0.319 | 0.301 | 0.028–3.200 | 0.685 | 0.428 | 1.985 | 0.364–10.81 |
| Yes | 3.322 | 0.313–35.71 | 0.504 | 0.093–2.747 | ||||
| Previous Stroke/TIA | ||||||||
| No | −16.711 | 0.988 | –a | –a | −0.852 | 0.176 | 0.427 | 0.124–1.464 |
| Yes | 2.342 | 0.683–8.065 | ||||||
| Cortical infarct on imaging | ||||||||
| No | −20.125 | <0.001 | –a | –a | −3.412 | <0.001 | 0.033 | 0.006–0.174 |
| Yes | 30.303 | 5.747–166.7 | ||||||
| Smoking | ||||||||
| No | −1.312 | 0.175 | 0.296 | 0.040–1.795 | −1.661 | 0.043 | 0.190 | 0.038–0.952 |
| Yes | 3.378 | 0.557–25.00 | 5.263 | 1.05–26.316 | ||||
| Small RLS | −0.205 | 0.801 | 0.814 | 0.165–4.009 | −1.008 | 0.143 | 0.365 | 0.095–1.406 |
| Large RLS | 1.229 | 0.249–6.061 | 1.575 | 0.711–10.53 | ||||
a
Odds ratio not calculable due to complete separation.
NS, no stroke; CS, cryptogenic stroke; NCS, non-cryptogenic stroke; TIA, transient ischemic attack; RLS, right-to-left shunt; PFO, patent foramen ovale; WBC, white blood cell count; HbA1c, glycated hemoglobin A1c.