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. 2025 Aug 21;16:1607131. doi: 10.3389/fmicb.2025.1607131

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Copyright © 2025 Liu, Cheng, Han, Xia, Wei, Chang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diagram showing an experiment timeline for 10-12 week-old male C57BL/6 mice. Mice are acclimatized for one week, then divided into four groups: (a) PBS with corn starch, (b) PBS with corn starch and rivaroxaban, (c) MCT with corn starch, and (d) MCT with corn starch and rivaroxaban. The timeline includes evaluations at -48, -24, 0, 6, 30, and 48 hours, with MCT administered at 0 hours and sacrifice at 48 hours. — Flowchart of the experimental design. (a) Control group; (b) RIV group; (c) MCT group; (d) MCT + RIV group.