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. 2025 Aug 21;16:1607131. doi: 10.3389/fmicb.2025.1607131

Figure 3.

Panel A shows liver images from four groups: Control, RIV, MCT, and MCT+RIV. Panel B contains bar graphs comparing levels of ALT, AST, T-BIL, D-BIL, and ALB across the same groups, with significant differences marked by asterisks. Panel C presents histological liver tissue images with detailed insets from each group. Panel D displays additional liver tissue histology images with magnified sections, highlighting differences among the groups.

Rivaroxaban ameliorated MCT-induced HSOS in mice. (A) Hepatic morphology (n = 5). (B) Serum liver function biochemical analysis. Statistical analysis was performed via ordinary one-way ANOVA. The data are presented as the means ± SEMs (n = 5). **p < 0.005, ***p < 0.001, ****p < 0.0001. (C) HE staining of liver tissues. Representative images from each group are shown (upper panel: 200 × magnification, scale bar = 100 μm; lower panel: 400 × magnification, scale bar = 100 μm) (n = 10). (D) Masson staining of liver tissues. Representative images from each group are shown (upper panel: 100 × magnification, scale bar = 200 μm; lower panel: 200 × magnification, scale bar = 100 μm) (n = 100). *p < 0.05..