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. 2025 Aug 21;16:1607131. doi: 10.3389/fmicb.2025.1607131

Figure 5.

Figure consists of four panels analyzing microbiota composition. Panel (a) shows a stacked bar chart with relative abundance of ten bacterial phyla across samples A to D, highlighting Firmicutes, Bacteroidetes, and others. Panel (b) displays mean proportions and confidence intervals for Actinobacteria, Firmicutes, and others between samples A and C, indicating significant proportion differences. Panel (c) is another stacked bar chart illustrating bacterial genera distribution across samples A to D, including Lactobacillus and Streptococcus. Panel (d) presents mean proportions and confidence intervals for Streptococcus and others between samples A, C, and D, showing significant differences.

Rivaroxaban modulates the gut microbial composition in MCT-HSOS model mice. (a) Taxonomic composition analysis at the phylum level. (b) Differentially abundant bacterial phyla between groups (p < 0.05, computed by STAMP). (c) Taxonomic composition analysis at the genus level. (d) Differentially abundant bacteria between groups (p < 0.05, computed by STAMP). Statistical analysis was performed using a two-sided Welch’s t-test. The data are expressed as the means with 95% CIs. (A. Control group, n = 5; B, RIV group, n = 6; C, MCT group, n = 6; D, MCT + RIV group, n = 5).