Table 1.

MCT-HSOS hepatic histology injury scores (DeLeve et al., 1999).

Central venule endothelial cell injury	Coagulative necrosis of liver cells	Subendothelial hemorrhage of the central vein	Hepatic sinusoidal hemorrhage
0, none	0, none	0, none	0, none
1, mild (Local involvement, but not all inner walls of endothelial vessels)	1, mild (Some but not all lobules are involved, or most lobules are not involved between lobules)	1, mild (Some but a few CVs are involved, or most CVs do not involve the interlobular area)	1, mild (The blood sinus in the central area of the lobule is involved, or most of the central area of the lobule is involved, but the interlobular area is not involved)
2, moderate (The whole inner wall of a few vessels is involved)	2, moderate (The lobular center is involved, and a few interlobular areas are involved)	2, moderate (Most CVs are involved, and some but a few CVs are involved in interlobular areas);	2, moderate (The central area of lobules is mostly involved, and a few lobules are involved in interlobular areas)
3, severity (The whole inner layer of the vessel is affected by most vessels)	3, severity (Most lobular centers are involved, and most interlobular areas are involved).	3, severity (Most CVs are involved, and most CVs are involved in interlobular areas).	3, severity (The central area of the lobule is mostly affected, and most of the lobules are involved in the interlobular area).