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. 2025 Aug 21;12:1632999. doi: 10.3389/fnut.2025.1632999

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Copyright © 2025 Ostaiza-Cardenas, Tobar, Costa, Calero, López-Carrera, Bermúdez and Orellana-Manzano.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Illustration of a balance scale with two sides. The left side shows icons representing DNA, a beetle, a person with genetics symbols, and a neuron, symbolizing negative metabolic and inflammatory processes. The right side shows icons of a person running and lifting weights, representing physical activity. Below, text states: “Regular physical activity induces epigenetic changes that can result in decreased expression of genes associated with negative inflammatory and metabolic processes”. — Relevance of physical activity and epigenetics.