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. 2025 Aug 22;16:1609815. doi: 10.3389/fneur.2025.1609815

Table 3.

Differences in physiological and biochemical indicators between the control group and treatment group before and after rehabilitation treatment.

Variables All patients (n = 80) Control group (n = 40) Treatment group (n = 40) p-value
NSE, Neuron-Specific Enolase (ng/mL)
Before rehabilitation treatment 20.38 (13.51–26.76) 20.37 (13.79–26.13) 20.46 (13.51–26.76) 0.43
After rehabilitation treatment 12.70 (8.37–17.26) 13.93 (10.35–17.26) 11.49 (8.37–16.63) 0.000757
NFL, Neurofilament light (pg/mL)
Before rehabilitation treatment 150.00 (110.31–195.19) 155.91 (110.31–194.49) 145.51 (120.36–195.19) 0.637
After rehabilitation treatment 66.86 (52.99–81.45) 71.83 (57.66–81.45) 61.95 (52.99–78.91) 9.73E-05
BDNF, Brain-Derived Neurotrophic Factor
Before rehabilitation treatment 7.49 (4.51–10.79) 7.49 (4.55–10.74) 7.39 (4.51–10.79) 0.977
After rehabilitation treatment 18.95 (9.49–31.66) 14.69 (9.49–29.42) 24.57 (10.09–31.66) 0.00378
SpO2, Oxygen Saturation (%)
Before rehabilitation treatment 93.05 (91.12–95.35) 92.80 (91.23–95.34) 93.20 (91.12–95.35) 0.686
After rehabilitation treatment 97.10 (95.24–98.79) 96.81 (95.24–98.79) 97.64 (95.28–98.75) 0.0304
Red Cell Distribution Width, RDW (%)
Before rehabilitation treatment 18.23 (15.74–20.00) 18.04 (16.04–19.92) 18.46 (15.74–20.00) 0.57
After rehabilitation treatment 12.96 (11.28–15.25) 13.70 (11.29–15.23) 12.66 (11.28–15.25) 0.0166
Platelet Count, PLT (× 109/L)
Before rehabilitation treatment 441.49 (353.29–513.52) 446.26 (353.29–513.52) 434.27 (353.76–512.95) 0.744
After rehabilitation treatment 280.19 (181.43–409.24) 312.49 (208.65–409.24) 253.44 (181.43–404.41) 0.00244
CRP, C-Reactive Protein (mg/L)
Before rehabilitation treatment 26.01 (18.55–35.96) 26.86 (19.19–35.54) 25.16 (18.55–35.96) 0.465
After rehabilitation treatment 7.82 (4.33–12.31) 9.45 (4.33–12.31) 7.12 (4.44–11.37) 0.000286
IL-10, Interleukin-10 (pg/mL)
Before rehabilitation treatment 23.65 (13.52–31.90) 22.70 (14.06–31.90) 25.29 (13.52–31.90) 0.482
After rehabilitation treatment 7.03 (3.62–9.58) 6.54 (3.62–9.53) 7.94 (4.12–9.58) 0.00453
IL-6, Interleukin-6 (pg/mL)
Before rehabilitation treatment 20.29 (13.21–28.60) 20.50 (13.21–28.60) 20.23 (13.31–28.29) 0.817
After rehabilitation treatment 5.63 (3.20–8.58) 6.63 (3.20–8.58) 4.91 (3.21–8.19) 0.0026