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. 2025 Aug 22;16:1634834. doi: 10.3389/fimmu.2025.1634834

Table 5.

Univariate and multivariate regression analysis of PFS.

Factor Univariate Multivariate
HR1 95%CI1 P-value HR1 95%CI1 P-value
Treatment methods2 0.991 0.517, 1.901 0.978 -
Tumor size(cm) 1.025 0.903, 1.163 0.705
Age 0.967 0.931, 1.005 0.086 0.977 0.924, 1.034 0.420
BMI 1.078 0.970, 1.198 0.145 1.101 0.932, 1.301 0.259
Gender 0.969 0.443, 2.119 0.937
Marital status 0.565 0.135, 2.365 0.434
Clinical Stages 1.228 0.574, 1.254 0.102 1.400 0.815, 2.404 0.897
T stage 0.828 0.738, 1.594 0.373
N stage 1.296 0.895, 1.877 0.170 1.022 0.591, 1.765 0.939
M stage 1.706 0.828, 3.513 0.148 0.455 0.092, 2.244 0.901
Complication 0.839 0.438, 1.607 0.596
Tumor location 1.075 0.769, 1.504 0.671
Year of diagnosis 0.508 0.254, 1.018 0.056 1.042 0.564, 1.924 0.031

PFS, progression free survival; OS, overall survival. Complication, including hypertension, diabetes mellitus, chronic obstructive pulmonary disease, pneumonia, cerebral infarction, coronary atherosclerotic heart disease. Tumor location, are esophageal cancer segments. In the multivariate analysis, bold values indicate P < 0.2, while in the univariate analysis table, bold values indicate P < 0.05.