Table 3. Receiver operating characteristics analysis table showing cut-off values of first trimester and diagnosis week TACPR indices in predicting clinical outcomes associated with ICP and CAPO.

Variable	Group	Outcome	AUC	Std. error	Sensitivity	Specificity	Asymp. Sig*	95% CI		Cut-off value
								Lower	Upper
First trimester TACPR	All	ICP	0.806	0.030	68.4%	68%	<0.001	0.747	0.864	1.35
First trimester TACPR	All	CAPO	0.759	0.048	65.6%	65.7%	<0.001	0.665	0.853	1.81
TACPR at diagnosis week	ICP	Severe ICP	0.774	0.055	69.2%	70.8%	<0.001	0.666	0.881	27.7
TACPR at diagnosis week	All	CAPO	0.807	0.045	75%	74.1%	<0.001	0.719	0.896	7.15

AUC: Area under the curve, CI: Confidence interval, ICP: Intrahepatic cholestasis of pregnancy, TACPR: Transaminase complex-platelet ratio, CAPO: Composite adverse perinatal outcomes

*Significance threshold: p<0.05