Table 5. Multivariate logistic regression analysis table showing independent risk factors associated with the occurrence of CAPO in cases of ICP.
|
Outcome: CAPO (group: ICP, n=98) | |||
|
Independent risk factors |
OR |
95% CI |
p-value* |
|
TACPR >5 at first trimester |
3.06 |
1.06-8.83 |
0.038 |
|
TACPR >50 at diagnosis week |
4.38 |
1.44-13.30 |
0.009 |
|
Severe ICP |
4.08 |
1.39-11.93 |
0.010 |
CAPO: Composite adverse perinatal outcomes, CI: Confidence interval, ICP: Intrahepatic cholestasis of pregnancy, OR: Odds ratio, TACPR: Transaminase complex–platelet ratio. Nagelkerke R²=0.477; Hosmer and Lemeshow test: χ²=1.632; df=4; p=0.803.
*Significance threshold: p<0.05