Table 4.
The results of the enrichment analysis of the differential metabolites
| Pathway | Total | Hits | Raw_p | FDR | Impact |
|---|---|---|---|---|---|
| Valine, leucine, and isoleucine biosynthesis | 23 | 1 | 0.05006 | 0.08224 | 0.0434782608696 |
| Histidine metabolism | 47 | 1 | 0.1001 | 0.1278 | 0.0212765957447 |
| Valine, leucine, and isoleucine degradation | 42 | 1 | 0.08983 | 0.1215 | 0.0238095238095 |
| Fructose and mannose metabolism | 54 | 1 | 0.1142 | 0.1314 | 0.0185185185185 |
| Phenylalanine, tyrosine, and tryptophan biosynthesis | 35 | 3 | 3.885e-05 | 0.0001489 | 0.0857142857143 |
| Glycine, serine, and threonine metabolism | 50 | 1 | 0.1061 | 0.1285 | 0.02 |
| Phenylalanine metabolism | 60 | 2 | 0.006874 | 0.01757 | 0.0333333333333 |
| beta-Alanine metabolism | 32 | 1 | 0.06907 | 0.1059 | 0.03125 |
| Aminoacyl-tRNA biosynthesis | 52 | 4 | 1.783e-06 | 1.025e-05 | 0.0769230769231 |
| mTOR signaling pathway | 4 | 1 | 0.008861 | 0.02038 | 0.25 |
| C-type lectin receptor signaling pathway | 11 | 1 | 0.02421 | 0.0464 | 0.0909090909091 |
| 2-Oxocarboxylic acid metabolism | 134 | 4 | 8.047e-05 | 0.0002644 | 0.0298507462687 |
| Serotonergic synapse | 42 | 1 | 0.08983 | 0.1215 | 0.0238095238095 |
| Biosynthesis of amino acids | 128 | 5 | 1.279e-06 | 9.809e-06 | 0.0390625 |
| Protein digestion and absorption | 47 | 4 | 1.179e-06 | 9.809e-06 | 0.0851063829787 |
| Mineral absorption | 29 | 3 | 2.18e-05 | 0.0001003 | 0.103448275862 |
| ABC transporters | 137 | 3 | 0.002281 | 0.006559 | 0.021897810219 |
| Shigellosis | 16 | 1 | 0.03505 | 0.06202 | 0.0625 |
| African trypanosomiasis | 8 | 1 | 0.01766 | 0.03692 | 0.125 |
| Central carbon metabolism in cancer | 37 | 4 | 4.39e-07 | 9.809e-06 | 0.108108108108 |