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. 2025 Jul 29;23(5):409–424. doi: 10.18502/ijrm.v23i5.19264

Table 2.

Comparative evaluation of outcomes between the 2 methods of endometrial preparation using HRC and mNC

Variables Group P-value
mNC-FET group HRC group
HCG positive rate# 25/56 (44.6) 27/63 (42.9) 0.845
Biochemical pregnancy rate# 4/56 (7.1) 6/63 (9.5) 0.640
Implantation rate# 22/102 (21.5) 21/112 (18.7) 0.602
Clinical pregnancy rate# 21/56 (37.5) 18/63 (28.6) 0.282
Ongoing pregnancy rate# 20/56 (35.7) 16 /63 (25.4) 0.221
Ectopic pregnancy rate# 0/56 (0) 2/63 (3.2) 0.497
Twin pregnancy rate# 1/56 (1.8) 2/63 (3.2) 0.999
Early miscarriage rate# 1/21 (4.8) 2/18 (11.1) 0.634
Cycle cancellation rate# 5/61 (8.2) 1/64 (1.6) 0.109
Number of visit## 2.80 ± 0.51 3 (2.25–3) 3.17 ± 0.58 3 (3–3) 0.001*
#Data presented as n (%), Chi-square test. ##Data presented as Mean ± SD and MD (IQR), Mann-Whitney U test. *Significant at the level of 0.05. HCG: Human chorionic gonadotropin, mNC: Modified natural cycle, HRC: Hormone replacement cycle, FET: frozen-thawed embryo transfer