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. 2025 Aug 6;17(8):e89483. doi: 10.7759/cureus.89483

Table 2. Intervention Effect on the Perception of Anxiety, Pain, and Satisfaction.

* Pre-intervention anxiety score was used for calculations

Variable Guided Meditation (N=31) Music (N=30) Nature Sounds (N=30) Control (N=30) P-value (Across All Four Groups) Combined Intervention Cohort (N=91) P-value (Between the Combined Intervention Cohort and Control)
Before injection
Pre-intervention anxiety 3.37 ± 3.13 2.27 ± 1.93 3.97 ± 3.03 2.47 ± 1.93 p=0.133 3.20 ± 2.82 p=0.371
Post-intervention (before IVI) anxiety 2.27 ± 2.63 1.35 ± 1.42 2.80 ± 2.57 - * p=0.086 2.14 ± 2.33 p=0.175
Change in anxiety score (pre- vs. post-intervention, pre-IVI) -1.10 ± 1.51 (p<0.001) -0.92 ± 1.05 (p<0.001) -1.17 ± 1.37 (p<0.001) - - -1.06 ± 1.32 (p<0.001) -
After injection
Post-IVI anxiety 2.48 ± 2.76 1.90 ± 2.01 2.93 ± 2.75 2.57 ± 2.47 p=0.566 2.44 ± 2.54 p=0.606
Change in anxiety score (pre-intervention vs. post-IVI) -0.89 ± 2.24 (p=0.024) -0.37 ± 1.67 (p=0.243) -1.03 ± 1.73 (p=0.002) 0.10 ± 1.75 p=0.081 -0.76 ± 1.90 (p<0.001) p=0.028
Pain 1.68 ± 2.51 1.52 ± 2.07 1.48 ± 1.88 2.32 ± 2.93 p=0.702 1.56 ± 2.15 p=0.279
Satisfaction 9.42 ± 1.20 9.30 ± 1.76 9.43 ± 1.22 9.57 ± 1.30 p=0.661 9.38 ± 1.40 p=0.215