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. 2025 Aug 14;6(4):100494. doi: 10.1016/j.xhgg.2025.100494

Figure 4.

Figure 4

Spatial transcriptomics to identify pyruvate metabolism in HCC

(A and C) Spatial distribution of 9 distinct clusters identified in HCC-1L and HCC-3L.

(B and D) FeaturePlot of pyruvate metabolism in the spatial organization of HCC-1L and HCC-3L.

(E and F) Spatiotemporal trajectory analysis of in HCC-1L.

(G and H) Spatiotemporal trajectory analysis of in HCC-3L.

(I and J) Correlation analysis between pyruvate metabolism genes and spatial trajectory scores in HCC-1L and HCC-3L.