Table 1.
Baseline characteristics.
| Baseline characteristics | Overall N = 5772 | Surgery N = 1411 | No surgery N = 4361 | p-value |
|---|---|---|---|---|
| Age (years) | 62.0 (12.5) | 58.8 (11.9) | 63.1 (12.6) | <0.0001 |
| Sex | ||||
| Male | 3685 (63.8%) | 936 (66.3%) | 2749 (63.0%) | 0.0249 |
| Female | 2087 (36.2%) | 475 (33.7%) | 1612 (37.0%) | |
| Medical history | ||||
| Hypertension | 3984 (69.0%) | 961 (68.1%) | 3023 (69.3%) | 0.3924 |
| Previous stroke | 883 (15.3%) | 167 (11.8%) | 716 (16.4%) | <0.0001 |
| Coronary artery disease | 157 (2.7%) | 43 (3.0%) | 114 (2.6%) | 0.3843 |
| Other heart disease | 197 (3.4%) | 41 (2.9%) | 156 (3.6%) | 0.2273 |
| Atrial fibrillation | 64 (1.1%) | 11 (0.8%) | 53 (1.2%) | 0.1743 |
| Diabetes mellitus | 535 (9.3%) | 131 (9.3%) | 404 (9.3%) | 0.9818 |
| Hypercholesterolaemia | 118 (2.0%) | 26 (1.8%) | 92 (2.1%) | 0.5373 |
| Current smoker | 1169 (20.3%) | 319 (22.6%) | 850 (19.5%) | 0.0113 |
| Current alcohol consumption | 1161 (20.1%) | 316 (22.4%) | 845 (19.4%) | 0.0139 |
| Modified Rankin scale score of 0 before onset | 4434 (76.8%) | 1127 (79.9%) | 3307 (75.8%) | <0.0001 |
| Medication at arrival | ||||
| Antihypertensive medication | 2472 (42.8%) | 563 (39.9%) | 1909 (43.8%) | 0.0106 |
| Blood glucose lowering agents | 371 (6.4%) | 92 (6.5%) | 279 (6.4%) | 0.8704 |
| Statin or other lipid lowering agent | 119 (2.1%) | 26 (1.8%) | 93 (2.1%) | 0.5054 |
| Aspirin or other antiplatelet agent | 277 (4.8%) | 82 (5.8%) | 195 (4.5%) | 0.0407 |
| Anticoagulation agent | 43 (0.7%) | 6 (0.4%) | 37 (0.8%) | 0.1081 |
| Systolic Blood Pressure (mmHg) | 173.5 (27.4) | 175.6 (29.2) | 172.9 (26.7) | 0.0269 |
| Diastolic Blood Pressure (mmHg) | 98.8 (17.3) | 99.6 (18.0) | 98.5 (17.1) | 0.3415 |
| NIHSS at admission | 13.0 (6.0, 22.0) | 22.0 (14.0, 32.0) | 11.0 (5.0, 18.0) | <0.0001 |
| GCS score | 12.0 (9.0, 14.0) | 9.0 (6.0, 12.0) | 13.0 (11.0, 15.0) | <0.0001 |
| Randomised group, n (%) | ||||
| Intervention | 2598 (45.0%) | 631 (44.7%) | 1967 (45.1%) | 0.8009 |
| Control | 3174 (55.0%) | 780 (55.3%) | 2394 (54.9%) | |
| Brain imaging features | ||||
| Volume of haematoma at baseline | 15.0 (8.0, 30.0) | 39.0 (25.0, 50.0) | 10.0 (5.7, 20.0) | <0.0001 |
| Location of haematoma | ||||
| Deep, n (%) | 4776 (82.8%) | 1168 (82.9%) | 3608 (82.8%) | 0.9404 |
| Cortical, n (%) | 494 (8.6%) | 180 (12.8%) | 314 (7.2%) | <0.0001 |
| Cerebellum, n (%) | 302 (5.2%) | 91 (6.5%) | 211 (4.8%) | 0.0180 |
| Brainstem, n (%) | 289 (5.0%) | 17 (1.2%) | 272 (6.2%) | <0.0001 |
| Intraventricular haematoma, n (%) | 1420 (24.6%) | 468 (33.2%) | 952 (21.8%) | <0.0001 |
Data are n (%), mean (SD), or median (IQR).
BP, denoted blood pressure; GCS, Glasgow coma scale; NIHSS, National Institutes of Health stroke scale.