Table 3.
Functional outcomes in 6 months follow-up.
| Outcomes | Surgery | No surgery | Unadjusteda |
Adjustedb |
PSMc |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | OR (95% CI) | p-value | ICC | N | aOR (95% CI) | p-value | ICC | N | aOR (95% CI) | p-value | ICC | |||
| Primary outcome | ||||||||||||||
| mRS 5–6 | 449/1222 (36.7%) | 738/3853 (19.2%) | 5075 | 2.60 (2.24–3.03) | <0.0001 | 0.025 | 4962 | 0.71 (0.55–0.92) | 0.010 | 0.013 | 2126 | 0.74 (0.56–0.98) | 0.034 | 0.027 |
| Secondary outcomes | ||||||||||||||
| mRS 4–6 | 695/1222 (56.9%) | 1150/3853 (29.9%) | 5075 | 3.34 (2.90–3.85) | <0.0001 | 0.026 | 4962 | 1.04 (0.82–1.33) | 0.732 | 0.011 | 2126 | 1.06 (0.81–1.37) | 0.671 | 0.030 |
| Death at 6 months | 243/1278 (19.0%) | 436/3949 (11.0%) | 5227 | 2.08 (1.73–2.50) | <0.0001 | 0.034 | 5108 | 0.55 (0.40–0.75) | 0.0001 | 0.027 | 2214 | 0.52 (0.37–0.72) | 0.0001 | 0.044 |
Note: aOR, denotes adjusted odds ratio; CI, confidence interval; ICC, intraclass correlation coefficient; mRS, modified Rankin Scale; OR, odds ratio.
Un-adjusted analysis: logistic regression for death/disability with a random effect for cluster (hospital site), a fixed effect indicating the group assignment of each cluster at each step, and a fixed categorical effect of 6-month interval.
Model adjusted baseline characteristics including mRS before stroke, age, sex, baseline NIHSS score, baseline haematoma volume, baseline systolic blood pressure, location of haematoma, intraventricular haemorrhage, previous history of stroke, current smoker and current alcohol user, and hospital management variables during including admission ward, BP lowering treatment (intravenous or oral), insulin treatment, antipyrexia treatment, anticoagulant reversal treatment (administrated PCC, FFP or VitK), Mechanical ventilation, and assist feeding.
Model adjusted for unbalanced baseline variables SD > 0.10 include baseline NIHSS score, baseline haematoma volume, presence of intraventricular haemorrhage and further hospital management variables including admission ward, BP lowering treatment (intravenous or oral), insulin treatment, antipyrexia treatment, anticoagulant reversal treatment (administrated PCC, FFP or VitK), Mechanical ventilation, and assist feeding.