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. 2002 Sep;13(9):3218–3234. doi: 10.1091/mbc.E02-03-0134

Figure 8.

Figure 8

Effect of selective and nonselective inhibitors of PKC on cytokine-induced changes in RT, Papp, and JAM and ICAM-1 expression. Cultures were exposed to TNF-α and IFN-γ in the presence or absence of H7 (nonselective) or chelerythrine chloride (selective) inhibitors of PKC. (A) RT and (B) Papp to 10-kDa FITC-dextran. JAM (C) and ICAM-1 (D) protein expression by ELISA in cultures treated with TNF-α and IFN-γ for 72 h in the absence or presence of 10 μM or 30 μM H7. *Significantly different from vehicle at p < 0.05. Data presented are a minimum of n = 12 cultures from at least three patients.