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. 2025 Apr 20;48(9):zsaf107. doi: 10.1093/sleep/zsaf107

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Figure 2. — Basal plasma corticosterone in male (left panel) and female (right panel) sleep-restricted (SR) rats compared to ambulation controls (AC) during the abstinence phase of prior opioid exposure (Opioids) or vehicle (Control) treatment. Individual values are displayed in dot plots with a box showing the median and range of the 25th to 75th percentiles. (a) p < .001 and p = .006 for male AC-SR differences within Control or Opioid treatments, respectively, and (b) p < .001 for the overall main effect of sex indicated by the vertical line with caps located at the means. N = 8 per group per sex.