Table 3.

Cox proportional hazard regression analyses for bladder-intact disease-free survival

Parameter	Univariable analysis		Multivariable analysis
	Hazard ratio (95% confidence interval)	p-value	Hazard ratio (95% confidence interval)	p-value
Age	0.948 (0.845 – 1.064)	0.363
Gender
Male	Reference
Female	0.535 (0.064 – 4.494)	0.565
Tumor stage
T2	Reference
T3	5.786 (1.289 – 25.980)	0.022	12.531 (2.038 – 77.050)	0.006
Node stage
N0	Reference
N1	0.044 (0 – 93005)	0.674
Multiple tumors
No	Reference
Yes	0.685 (0.151 – 3.111)	0.624
Immunotherapy
No	Reference
Yes	0.176 (0.029 – 1.057)	0.058	0.074 (0.009 – 0.624)	0.017