TABLE 3.
UVA/MVA of Sociodemographic, Comorbidity, and Clinical Characteristics Associated With Poorly Versus Well/Moderately Differentiated Tumors
| Characteristic | UVA—OR (95% CI) | P | MVA—OR (95% CI) | P |
|---|---|---|---|---|
| ADI | ||||
| 1_3 | Reference | <0.001 | Reference | 0.022 |
| 4–10 | 1.40 (1.22–1.60) | 1.23 (1.03–1.48) | ||
| Age | ||||
| <49 | Reference | <0.001 | Reference | 0.10 |
| 50–69 | 0.75 (0.64–0.87) | 0.80 (0.66–0.98) | ||
| >70 | 0.67 (0.56–0.81) | 0.87 (0.68–1.11) | ||
| Race | ||||
| White | Reference | <0.001 | Reference | 0.027 |
| Black | 2.26 (1.89–2.71) | 1.46 (1.14–1.87) | ||
| Asian | 1.34 (1.09–1.65) | 1.03 (0.79–1.35) | ||
| Other | 1.43 (1.16–1.77) | 1.07 (0.81–1.40) | ||
| Hispanic ethnicity | ||||
| No | Reference | 0.3 | ||
| Yes | 1.11 (0.89–1.38) | |||
| Insurance | ||||
| Private or Medicare | Reference | 0.008 | Reference | 0.6 |
| Medicaid | 1.27 (1.06–1.51) | 1.07 (0.85–1.34) | ||
| BMI | ||||
| Normal | Reference | 0.03 | Reference | 0.5 |
| Overweight | 1.01 (0.86–1.19) | 0.92 (0.74–1.13) | ||
| Obese | 1.21 (1.03–1.42) | 1.03 (0.83–1.28) | ||
| Alcohol use | ||||
| Never | Reference | 0.015 | Reference | 0.6 |
| Socially | 0.99 (0.86–1.13) | 0.99 (0.82–1.18) | ||
| Frequently | 0.58 (0.39–0.84) | 0.80 (0.49–1.35) | ||
| Smoking | ||||
| No | Reference | <0.001 | Reference | 0.014 |
| Yes | 1.32 (1.13–1.51) | 1.26 (1.02–1.54) | ||
| Clinical stage | ||||
| 1 | Reference | <0.001 | Reference | <0.001 |
| 2 | 2.32 (2.01–2.69) | 1.76 (1.47–2.12) | ||
| 3 | 3.44 (2.53–4.69) | 2.82 (1.9–4.20) | ||
| Tumor subtype | ||||
| ER+/HER2− | Reference | <0.001 | Reference | <0.001 |
| ER+/HER2+ | 4.04 (3.13–5.24) | 3.49 (2.65–4.61) | ||
| ER−/HER2+ | 14.2 (9.05–23.1) | 12.5 (7.78–21.1) | ||
| ER−/HER2− | 20.0 (15.0–27.2) | 17.6 (13.0–24.4) | ||
BMI indicates body mass index; MVA, multivariable; UVA, univariable.