Table 3.
Relationships between the expression of CXCL14 and clinicopathological parameters
| Age | |||||
| <75 y (n = 151) | ≥75 y (n = 7) | P value | |||
| IHC score | 21.3±20.3 | 8.4±6.0 | 0.000 | ||
| Gender | |||||
| Female | Male | P value | |||
| IHC score | 19.6±18.2 | 21.7±21.5 | 0.513 | ||
| Stage | |||||
| I | II | III | IV | P value | |
| IHC score | 32.4±21.2 | 20.4±18.8 | 19.0±20.6 | 18.2±19.0 | 0.0309 |
| Differentiation of cancer cells | |||||
| W/D | M/D | P/D | P value | ||
| IHC score | 25.9±21.5 | 21.0±20.9 | 18.7±15.2 | 0.2786 | |
| Depth of tumor invasion (T stage) | |||||
| 1 | 2 | 3 | 4 | P value | |
| IHC score | 32.5±21.0 | 29.0±19.8 | 20.6±20.6 | 12.6±14.8 | 0.0076 |
| Nodal metastasis (N stage) | |||||
| Absent | Low (1-3) | High (≥4) | P value | ||
| IHC score | 21.8±19.4 | 20.9±23.7 | 18.4±17.8 | 0.2318 | |
| Distant metastasis | |||||
| Negative | Positive | P value | |||
| IHC score | 22.6±21.0 | 16.3±17.3 | 0.151 | ||
| Perineural tumor invasion | |||||
| Negative | Positive | P value | |||
| IHC score | 23.0±21.5 | 15.4±14.5 | 0.251 | ||
| Tumor budding | |||||
| Absent | Low (5-9/10HPF) | High | P value | ||
| IHC score | 23.2±19.4 | 25.4±21.8 | 12.2±12.8 | 0.179 | |
IHC, immunohistochemistry.