Fig 2.
Effect of QHGAD67 on Fos-LI in dorsal horn. (A) Fos-LI in dorsal horn induced by 10 minutes of gentle tactile stimulation was markedly increased in rats inoculated with QOZHG 1 week after spinal nerve ligation (SNL) and tested 2 weeks later (3 weeks after SNL). (B) This increase was blocked in rats with SNL that had been inoculated with QHGAD67 1 week after SNL and tested 2 weeks later (3 weeks after SNL), and it was found in laminae I–VI of dorsal horn. Results are expressed as mean ± standard error of the mean. **p < 0.01; n = 5 animals per group. The difference between sham-operated and SNL animals inoculated with QOZHG was also statistically significant (p < 0.01).