Table 1.
Thymic findings in mice according to their age of kRAS mutation inoculation
| Mice | Sex | Age at inoculation (months) | Medullary portion ± | C:M ratio* | Adipose involution |
|---|---|---|---|---|---|
| 16KYP12 | Male | 1.2 | + | 80:20 | No |
| 28KYP13 | Female | 1.2 | + | 60:40 | No |
| 11KYP12 | Male | 1.2 | + | Atrophic | Yes |
| 7KY23 | Male | 1.5 | + | 60:40 | No |
| 2KY23 bis | Female | 1.5 | – | ND | Yes (cystic lesion) |
| 4KY23 bis | Female | 1.5 | + | 50:50 | No |
| 5KY24 bis | Male | 1.5 | + | 30:70 | No |
| 7KY7 bis | Female | 1.7 | + | 50:50 | Yes |
| 6KY43° | Female | 2 | + | 30:70 | No |
| 1KY19 | Male | 2.2 | + | 90:10 | No |
| 4KY20 | Female | 2.2 | + | 40:60 | No |
| 6KY19 | Male | 2.2 | + | 80:20 | No |
| 5KY20 | Female | 2.2 | + | 60:40 | No |
| 3KY42 | Male | 2.6 | + | 60:40 | no |
| 4KY42 | Male | 2.6 | + | 60:40 | No |
| 2KY42 | Male | 2.6 | + | 60:40 | No |
| 17 KY7 bis | Female | 4.8 | + | 80:20 | No |
| 3KY7bis | Female | 4.8 | – | ND | Yes |
| 25KY7 bis | Female | 4.8 | – | ND | Yes |
°control
*cortical: medullary ratio (positive for the thymus presence when equal or greater than 50:50