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. 2025 Aug 27;16:1646038. doi: 10.3389/fimmu.2025.1646038

Table 2.

Multivariable logistic regression analysis.

Variables Coef. SE z.value p.value OR (95%CI)
Intercept -5.926 0.096 -61.576 < 0.001* 0.003 (0.002-0.003)
Age
≥ 65 years 0.35 0.12 2.917 0.003* 1.419 (1.115-1.805)
Gender
Male -0.172 0.06 -2.874 0.004* 0.842 (0.748-0.946)
Drugs
Pembrolizumab 1.83 0.109 16.847 < 0.001* 6.231 (5.008-7.669)
Nivolumab 1.248 0.116 10.785 < 0.001* 3.483 (2.757-4.342)
Carboplatin 0.814 0.143 5.71 < 0.001* 2.256 (1.687-2.952)
Enfortumab Vedotin 3.985 0.184 21.614 < 0.001* 53.76 (36.815-76.003)
Ipilimumab 1.344 0.204 6.584 < 0.001* 3.833 (2.502-5.589)
Bendamustine 1.84 0.201 9.167 < 0.001* 6.299 (4.144-9.134)
Atezolizumab 0.919 0.187 4.927 < 0.001* 2.507 (1.702-3.546)
Vemurafenib 2.264 0.198 11.461 < 0.001* 9.618 (6.375-13.869)
Pemetrexed 1.665 0.187 8.881 < 0.001* 5.285 (3.582-7.489)
Apalutamide 2.589 0.238 10.885 < 0.001* 13.311 (8.072-20.61)

OR, odds ratio; CI, confidence interval. The analysis was adjusted for age (reference: <65 years), gender (reference: female), and drugs (reference: all other anticancer drugs). * p < 0.01.