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. 2025 Sep 10;40(1):192. doi: 10.1007/s00384-025-04991-x

Table 5.

Crohn’s disease characteristics

Elderly patients (EPs), n = 30 Young patients (YPs) n = 60 p
Initial type of diagnosed IBD 0.05
Ulcerative colitis, n (%) 8 (26.7%) 5 (8.3%)
Crohn’s disease, n (%) 21 (70%) 54 (90%)
Indetermined colitis, n (%) 1 (3.3%) 1 (1.7%)
Crohn’s disease localization* 0.003
L1 ileal, n (%) 1 (3.3%) 14 (23.3%)
L2 colonic, n (%) 21 (70%) 20 (33.3%)
L3 ileo-colonic, n (%) 8 (26.7%) 25 (41.7%)
Anoperineal with no luminal involvement, n (%) 0 (0%) 1 (1.7%)
Rectal involvement n (%) 23 (76.7%) 34 (56.7%) 0.06
Crohn’s disease phenotype* 0.23
B1 inflammatory, n (%) 21 (70%) 37 (61.7%)
B2 stricturing§, n (%) 3 (10%) 16 (26.7%)
B3 penetrating§, n (%) 7 (23.3%) 9 (15%)
Extra-intestinal manifestations, n (%)‡ 1 (3.3%) 18 (30%) 0.004
rheumatological, n (%) 0/1 (0%) 11/18 (61.1%)
skin/mucosal, n (%) 0/1 (0%) 8/18 (44.4%)
Ocular, n (%) 0/1 (0%) 1/18 (5.6%)
Other∫, n (%) 1/1 (100%) 0/18 (0%)

IQR interquartile range, EPs age at first surgery ≥ 60, YPs age at first surgery < 60, IBD inflammatory bowel disease

*According to Montreal Classification12

§1 EP and 2 YPs had both stricturing and penetrating forms

‡2 patients had 2 types of extra-intestinal manifestations simultaneously: one presented with both cutaneous-mucosal and articular manifestations, while the other presented with ocular and articular manifestations

∫The only EP who had an extra-intestinal manifestation, had a diagnosis of primary sclerosing cholangitis