Table 2. Relationship of systemic neutrophilic inflammation with lung function.
| Dataset | Variable | Relationship with change in absolute FEV1% | |
|---|---|---|---|
| Spearman correlation | Unadjusted p value | ||
| Immune cells | Neutrophils | 0.041 | 0.775 |
| Neutrophil cell surface markers | CD101 | 0.056 | 0.713 |
| Neutrophil cell surface markers | CXCR4** | −0.444 | 0.001 |
| Neutrophil cell surface markers | CD206 | −0.162 | 0.260 |
| Neutrophil cell surface markers | CD15 | −0.156 | 0.278 |
| Neutrophil cell surface markers | CD16* | −0.311 | 0.028 |
| Neutrophil cell surface markers | CD66b | −0.272 | 0.056 |
| Cytokines | IL3 | 0.026 | 0.860 |
| Cytokines | IL6 | −0.144 | 0.322 |
| Cytokines | IL8 | −0.219 | 0.131 |
| Cytokines | G-CSF | −0.132 | 0.368 |
| Cytokines | CXCL5 | 0.252 | 0.081 |
| Cytokines | CXCL1 | 0.009 | 0.951 |
*
p<0.05, **p<0.01.
FEV1, forced expiratory volume in 1 s; G-CSF, granulocyte-colony stimulating factor.