Table 1.
Summary of DSC3 expression and methylation state in primary breast tumors
| Cell/tumor | Expressiona | Methylationb | %Mec | Age (years) | Histology |
| HMEC | 100.0% | - | 15 | N/A | N/A |
| MCF10A | 150.0% | - | 7 | N/A | N/A |
| 120T | 81.4% | - | 3 | 59 | IDC |
| 7732T | 6.9% | - | 10 | 44 | IDC |
| 6385T | 0.0% | ++ | 69 | 70 | IDC |
| 173T | 0.1% | + | 30 | 55 | IDC |
| 8900T | 77.2% | - | 2 | 56 | IDC |
| 4658T | 52.4% | - | 8 | 83 | IDC |
| 7768T | 2.3% | - | 7 | 40 | IDC |
| 2504T | 67.8% | - | 16 | 53 | IDC |
| 9613T | 8.0% | - | 9 | 42 | IDC |
| 6010T | 0.3% | + | 21 | 55 | IDC |
| 2909T | 26.3% | - | 1 | 38 | IDC |
| 2845T | 0.0% | ++ | 49 | 77 | IDC |
| d5974-1T | 10.0% | + | 23 | 43 | IDC |
| d5974-2T | 10.0% | ++ | 48 | 43 | IDC |
| 7093T | 10.0% | + | 30 | 63 | IDC |
| 9068T | 0.0% | - | 8 | 73 | IDC |
| 4392T | 0.0% | + | 33 | 47 | IDC |
| 5799T | 0.0% | + | 22 | 53 | IDC |
| 6245T | 0.0% | - | 1 | 30 | IDC |
| 2405T | 30.0% | + | 20 | 58 | IDC |
| 2420T | 0.0% | - | 8 | 54 | IDC |
| 5256T | 3.9% | - | 1 | 60 | IDC |
| 1139T | 6.4% | - | 11 | 40 | IDC lymph node Met. |
| 9663T | 0.1% | + | 60 | 41 | IDC lymph node Met. |
| 9985T | 5.8% | - | 0 | 61 | ILC |
| 7788T | 1.3% | + | 23 | 76 | ILC |
| 6861T | 20.2% | + | 29 | 71 | ILC |
| 5358T | 73.9% | ++ | 58 | 42 | ILC |
| 6608T | 5.6% | - | 8 | 74 | ILC |
| 7491T | 30.0% | - | 2 | 64 | ILC |
| 6809T | 0.0% | ++ | 49 | 57 | ILC |
| 4099T | 0.6% | + | 37 | 43 | Mucoid ductal CA |
aRNA expression levels determined by quantitative real-time PCR and relative to human mammary epithelial cells (HMECs). bCpG island methylation levels determined by bisulfite sequencing: ++, >40% methylation of total CpG sites analyzed; +, >20% methylation of total CpG sites; -, <20% methylation of total CpG sites analyzed. cPercent methylation was calculated based on the number of methylated CpG sites compared to the total number of sites analyzed. dTwo independent tumors isolated from the same breast. IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; N/A, not applicable, IDC lymph node Met, invasive ductal carcinoma that metastasized to the lymph node, Mucoiod Ductal CA, mucinous ductal carcinoma.