Table 3.

Relationship between COX-2 and MDR1/P-gp (detected with C219 or JSB-1 antibodies) expression (Chi²-Test, P < 0.001)

	COX-2 positive cases	COX-2 negative cases	Sum
Entire study group (n = 104)
C219 low [IRS 0–3]	56	5	61
C219 high [IRS 4–12]	2	41	43
Sum	58	46	104
JSB-1 low [IRS 0–3]	55	4	59
JSB-1 high [IRS 4–12]	3	42	45
Sum	58	46	104
Patients postoperatively treated only with chemotherapy (n = 28)
C219 low [IRS 0–3]	13	1	14
C219 high [IRS 4–12]	1	13	14
Sum	14	14	28
JSB-1 low [IRS 0–3]	12	1	13
JSB-1 high [IRS 4–12]	2	13	15
Sum	14	14	28

COX-2, cyclooxygenase-2; MDR1/P-gp, MDR1/P-glycoprotein; IRS, immunoreactive score [17].