Table 1.

Patient, Tumor, and Treatment Characteristics of the Initial Patient Group, New Patient Group, and All Patients

	Initial Group (n = 54)		New Group (n = 86)		All Patients (N = 140)
Characteristic	No.	%	No.	%	No.	%	P *
Age, years
Mean	57.8		60.4		59.4		.24†
Sex
Male		74		84.9		80.7	.12‡
Tumor site							.34‡
Oral cavity	11	20	16	19	27	19
Oropharynx	31	57	39	45	70	50
Hypopharynx	8	15	22	26	30	22
Other	4	7	9	11	13	9
Tumor volume, cm2
Mean	27.5		20.9		23.7		.03†
Not available	5		18
T stage							.54‡
0–2	27	50	47	55	74	53
3–4	27	50	39	45	66	47
N stage							.07‡
0	7	13	21	25	28	20
1	1	2	6	7	7	5
2	35	65	51	59	86	61
3	11	20	8	9	19	14
Stage							.02‡
I-II	2	4	14	16	16	12.5
III-IV	52	96	72	84	124	88.5
Hemoglobin, g/dL
Mean	13.7		13.6		13.6		.8†
OPN level, ng/mL
Mean	490.6		559.3		532.8		.11†
Median	440.3		532.0		496.0
Surgery for primary		35		42		39	.48‡
Neck dissection		41		40		40	.93‡
Radiotherapy		93		78		83	.01‡
Chemotherapy		74		64		68	.20‡
Mean follow-up, months							.003†
All patients	39		27		32		< .0001†
Living patients	63		38		47
Patients with uncontrolled tumor	3	6	8	9	11	8	.42‡
Patients with relapse	23	43	27	31	50	36	.23‡
Patients who died	29	54	37	43	66	47	.22‡

Abbreviation: OPN, osteopontin.

^*P = between initial and new groups.

^†t test P.

^‡χ²P.