Table 3.
Results of multivariate Cox proportional hazard model analysis on freedom from relapse and overall survival
| FFR | Overall Survival | |||||
|---|---|---|---|---|---|---|
| Parameter | P | HRa | 95% CI | P | HR | 95% CI |
| Age (continuous) | 0.37 | 1.01/yr | 0.98–1.05 | 0.06 | 1.04/yr | 1.00–1.09 |
| OPN (≤450 versus >450 μg/ml) | 0.01 | 3.0 | 1.3–7.3 | 0.02 | 6.3 | 1.4–68.9 |
| Chemotherapy (yes versus no) | 0.18 | 0.53 | 0.2–1.3 | NA | NA | NA |
| Primary tumor site (oropharynx versus others) | 0.03 | 2.5 | 1.1–5.9 | NA | NA | NA |
| TV (≤28 versus >28 cm3) | NA | NA | NA | 0.46 | 1.6 | 0.5–5.0 |
| N-stage (0–2 versus 3) | NA | NA | NA | 0.007 | 5.3 | 1.6–17.7 |
a
HR, hazard ratio; CI, confidence interval; NA, not applicable. The parameter was not entered into the multivariate model because of its lack of significance on univariate analysis.