Table 2.
Genes identified involved in mitochondrial function
Gene | Function |
BCS1 | Cytochrome bc(1) complex biogenesis |
PDB1 | Pyruvate dehydrogenase activity |
DIA4 | Serine-tRNA ligase activity |
MTF1 | Mitochondrial RNA polymerase specificity factor |
PPA2 | Inorganic phosphatase |
MRPL35 | Mitochondrial ribosome subunit |
PET117 | Cytochrome oxidase assembly |
MRPL20 | Mitochondrial ribosome subunit |
NUC1 | DNA/RNA nuclease |
PTH1 | Peptidyl-tRNA hydrolase |
QCR2 | Ubiquinol cytochrome c reductase subunit |
MRP17 | Mitochondrial ribosome subunit |
RRF1 | Mitochondrial ribosome recycling factor |
RSM7 | Mitochondrial ribosome subunit |
COX10 | Heme a biosynthesis |
CBP3 | Ubiquinol cytochrome c reductase assembly |
CBP2 | Mitochondrial RNA splicing |
MSM1 | Methionyl-tRNA synthetase |
ATP10 | ATP synthase assembly |
CBP1 | Mitochondrial RNA processing |
MDL2 | ABC transporter |
YTA12 | Protein turnover |
IMP1 | Inner membrane protease subunit |
CYT2 | Cytochrome c1 heme lyase |
CBP4 | Ubiquinol-cytochrome c reductase assembly |
COQ5 | Ubiquinone biosynthesis |
COQ4 | Ubiquinone biosynthesis |
CTP1 | Inner membrane citrate transporter |
MRP13 | Mitochondrial ribosome subunit |
FIS1 | Mitochondrial division |