Table 2.

Comparisons of laboratory data and BMD measurements of children with chronic hepatitis B treated with IFN-alpha alone or combination with lamivudine and healthy controls.

Variables	Patients (n = 54)	Control (n = 50)	P
TNF-α	25.54 ± 8.30	15.47 ± 6.77	NS
IL-1β	7.32 ± 12.13	5.48 ± 6.14	NS
IL-2r	1403.07 ± 455.67	1120.48 ± 492.37	0.002
IL-6	25.21 ± 39.27	5.98 ± 6.49	0.001
IL-8	18.46 ± 14.77	12.55 ± 7.36	0.013
PTH	41.51 ± 28.80	33.08 ± 18.22	0.029
s-CTX	1.92 ± 0.76	1.61 ± 0.52	0.021
Osteocalcin	64.67 ± 30.63	75.81 ± 31.10	NS
Serum calcium	9.57 ± 1.83	9.49 ± 1.52	NS
ALP	221.27 ± 67.27	219.66 ± 78.74	NS
ALT	62.14 ± 88.31	27.01 ± 42.41	0.009
AST	58.41 ± 65.57	31.72 ± 29.69	0.007
L2–4 BMD	0.62 ± 0.13	0.59 ± 0.12	NS
Femur neck BMD	0.80 ± 0.16	0.72 ± 0.15	0.012
Trochanter BMD	0.68 ± 0.14	0.62 ± 0.14	0.046