Table 2. Baseline NLR association with treatment.
| Treatment | Lymphocyte_Count_1 (Mean ± SD) | Neutrophil_Count_1 (Mean ± SD) | Neutrophil-to-Lymphocyte ratio (Mean ± SD) | Beta | p-value (NLR) |
|---|---|---|---|---|---|
| Hydroxychloroquine | 2.25 ± 0.74 | 7.88 ± 4.20 | 8.33 ± 8.94 | −0.042 | 0.620 |
| Chloroquine | 2.02 ± 0.59 | 8.14 ± 4.42 | 8.86 ± 7.71 | −0.013 | 0.762 |
| Azithromycin | 2.36 ± 5.10 | 8.25 ± 4.52 | 8.81 ± 8.84 | −0.008 | 0.339 |
| Kaletra | 2.26 ± 0.90 | 8.12 ± 4.24 | 8.50 ± 7.89 | −0.029 | 0.602 |
| Tocilizumab | 2.17 ± 0.63 | 7.67 ± 4.00 | 8.27 ± 8.63 | −0.081 | 0.031** |
| Favipiravir | 2.25 ± 0.74 | 7.99 ± 3.88 | 9.01 ± 9.78 | −0.028 | 0.321 |
| Remdesivir | 1.93 ± 0.48 | 7.96 ± 3.38 | 9.82 ± 7.13 | −0.021 | 0.426 |
| Ribavirin | 2.22 ± 0.88 | 8.35 ± 4.74 | 9.20 ± 9.13 | −0.066 | 0.115 |
| IVIG | 2.21 ± 0.72 | 7.97 ± 4.76 | 7.68 ± 5.45 | −0.000 | 0.995 |
| Interferon | 2.31 ± 0.99 | 8.04 ± 4.42 | 8.12 ± 6.97 | 0.068 | 0.050 |
| Ostilomavir | 2.78 ± 9.22 | 8.02 ± 4.22 | 7.54 ± 5.33 | −0.091 | 0.004** |
| β-Lactam/BLI | 2.24 ± 0.77 | 7.79 ± 3.94 | 8.30 ± 8.24 | 0.054 | 0.055 |
| Cephalosporine | 2.46 ± 6.14 | 8.10 ± 4.57 | 8.38 ± 8.40 | −0.008 | 0.771 |
| Carbapenem | 2.50 ± 6.77 | 8.16 ± 4.24 | 8.48 ± 7.85 | −0.046 | 0.175 |
| Aminoglycosides | 2.46 ± 1.09 | 7.81 ± 3.23 | 8.38 ± 8.40 | −0.002 | 0.945 |
| Colistin | 2.28 ± 0.72 | 8.18 ± 4.22 | 8.24 ± 7.52 | −0.026 | 0.399 |
| Ceftalazone-Avibactam | 2.20 ± 0.61 | 9.40 ± 5.49 | 10.15 ± 10.56 | −0.020 | 0.506 |
| Ceftazidime-Tazobactam | 2.18 ± 0.48 | 9.37 ± 4.48 | 9.26 ± 8.27 | −0.012 | 0.667 |
| Vancomycin | 2.51 ± 7.21 | 8.15 ± 4.23 | 8.63 ± 7.84 | −0.021 | 0.476 |
| Linezolid | 2.22 ± 0.72 | 8.30 ± 4.43 | 9.44 ± 8.91 | −0.064 | 0.029** |
| Antifungal | 2.22 ± 0.59 | 7.91 ± 4.30 | 8.31 ± 8.49 | 0.007 | 0.796 |
Notes.
NLR values represent baseline measurements at ICU admission (Day 1). Significance (p-value) reflects differences in baseline NLR between patients who received the specified treatment versus those who did not, derived from a Generalized Linear Model (GLM) adjusted for age, gender, and comorbidities. This analysis does not evaluate longitudinal NLR changes post-treatment.
Shows statistical significance, p < 0.05.