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. 2025 Jun 25;16(3):571–587. doi: 10.1007/s13167-025-00415-6

Table 6.

Weighted odds ratios from logistic regression estimating the association between periodontitis and late age-related macular degeneration (AMD)

Variables Model 1* Model 2†
OR (95% CI) P-value OR (95% CI) P-value
Age (years)
40 to 64 Reference – Reference –
65 to 74 3.25 (1.77–5.96)  < 0.001 3.15 (1.68–5.90)  < 0.001
More than 75 6.31 (3.35–11.87)  < 0.001 5.92 (3.04–11.56)  < 0.001
Sex
Female – – Reference –
Male – – 2.14 (1.27–3.61) 0.004
Body mass index (kg/m2)
Less than 22.9 – – Reference –
23.0 to 24.9 – – 1.16 (0.63–2.13) 0.649
More than 25.0 – – 0.81 (0.42–1.53) 0.511
Diabetes Mellitus – – 0.30 (0.09–0.97) 0.045
Hypertension – – 1.52 (0.88–2.61) 0.134
Periodontitis 1.10 (0.66–1.85) 0.706 1.02 (0.61–1.71) 0.944

OR = odds ratio; CI = confidence interval

*Model 1: Adjusted for age only

†Model 2: Adjusted for age, sex, body mass index, diabetes, and hypertension