Table 2.

Treatment exposure in the EYELIGHT study

Total number of included subjects	136
Safety analysis (all injections, products and indications)	1376
Efficacy analysis (initial injections performed with R2 alone)	451

Treatment exposure (R2 only)
Average volume per subject and visit (mean ± sd)	0.52 ± 0.54 mL
Average volume per indication (mean ± sd)	0.32 ± 0.25 mL

Treated indications (R2 only)
Indication	Initial injections (n, % of all periorbital initial injections)	All injections (n, % of all periorbital injections)
Tear trough	89 (35.3%)	115 (37.2%)
Palpebromalar groove	61 (24.2%)	78 (25.2%)
Crow’s feet	38 (15.1%)	43 (13.9%)
Outer canthus	45 (17.9%)	53 (17.2%)
Brow	19 (7.5%)	20 (6.5%)

SD, standard deviation