Reagents and tools table
| Reagent/resource | Reference or source | Identifier or catalogue number |
|---|---|---|
| Experimental models | ||
| Human left ventricular myocardium | This study | N/A |
| Antibodies | ||
| Alexa Flour 647-conjugated wheat germ agglutinin | Molecular Probes | W32466 |
| Alexa Fluor 488 donkey anti-rabbit IgG | Thermo Fisher Scientific | ab15065 |
| Anti-ACTN2 mouse IgG | Sigma-Aldrich | A7732 |
| Anti-ALDOA rabbit IgG | Sigma-Aldrich | HPA004177 |
| Anti-ATP2A2/SERCA2 mouse IgG | Thermo Fisher Scientific | MA3919 |
| Anti-GFM1 rabbit IgG | Sigma-Aldrich | HPA061405 |
| Anti-NDUFS3 rabbit IgG | Abcam | ab177471 |
| Anti-TNNI3 (cardiac troponin I) rabbit IgG | Abcam | ab47003 |
| DyLight 550 IgG donkey anti-mouse IgG | Abcam | ab9879 |
| Chemicals, enzymes, and other reagents | ||
| Acetonitrile (HPLC grade) | Thermo Fisher Scientific | A955-4 |
| Ammonium formate | Sigma-Aldrich | 70221 |
| Chloroacetamide | Sigma-Aldrich | C0267 |
| Chloroform (HPLC grade) | Thermo Fisher Scientific | C606SK-1 |
| DAPI | Thermo Fisher Scientific | 62248 |
| DPX | Sigma-Aldrich | 06522 |
| Formic acid (LC-MS grade) | Thermo Fisher Scientific | A117-50 |
| Methanol (HPLC grade) | Thermo Fisher Scientific | A456-4 |
| Mito-ID | Enzo Life Sciences | ENZ-51022-0100 |
| Pierce™ BCA Protein Assay | Thermo Fisher Scientific | 23225 |
| ProLong Diamond antifade mountant | Thermo Fisher Scientific | P36970 |
| Qubit™ dsDNA High Sensitivity Quantification Assay Kit | Thermo Fisher Scientific | Q32851 |
| Sodium deoxycholate | Sigma-Aldrich | 30970 |
| Superfrost Plus slides | Menzel, Thermo Fisher Scientific | J1810AMNZ |
| TCEP | Thermo Fisher Scientific | 20490 |
| Tris-HCl pH 7.5 | Sigma-Aldrich | T5941 |
| Triton™ X-100 | Sigma-Aldrich | T8787 |
| TRIzol | Invitrogen | 15596026 |
| Trypsin (sequencing grade) | Promega | V5111 |
| Van Gieson’s stain | This study | N/A |
| Verhoeff’s Iron Haematoxylin solution | This study | N/A |
| Software | ||
| Adobe Illustrator | Adobe | Version 27.8 |
| BioRender | https://biorender.com | N/A |
| clusterProfiler | https://bioconductor.org/packages/clusterProfiler | Version 4.8.1 |
| DeepVenn | https://www.deepvenn.com/ | N/A |
| DIA-NN | https://github.com/vdemichev/DiaNN | Version 1.7 |
| Gene Ontology (GO) | https://geneontology.org/ | Version 3.17.0 |
| ggplot2 | https://github.com/tidyverse/ggplot2 | Version 3.4.2 |
| GraphPad Prism | GraphPad | Version 9.5.1 |
| Huygens Professional | Scientific Volume Imaging | Version 22.10.0p1 |
| ImageJ | ImageJ | Version 1.54f |
| KEGG | https://www.genome.jp/kegg/ | Version 102.0 |
| KEGGREST | https://github.com/Bioconductor/KEGGREST | Version 1.40.0 |
| limma | https://github.com/gangwug/limma | Version 3.56.2 |
| LipidSearch | Thermo Fisher Scientific | Version 4.2 |
| Microsoft Excel | Microsoft | Version 2309 |
| MitoCarta3.0 | Rath et al, (2021) | N/A |
| NIS-elements | Nikon | Version 4.0 |
| PANTHER | http://www.pantherdb.org | Version 17.0 |
| R | R | Version 4.3.1 |
| Rsubread | https://bioconductor.org/packages/release/bioc/html/Rsubread.html | Version 2.2.1 |
| SCIEX OS | AB Sciex | Version 1.7.0.36606 |
| scMerge | https://github.com/SydneyBioX/scMerge | Version 1.16.0 |
| SRplot | https://www.bioinformatics.com.cn/en | N/A |
| STRING | https://string-db.org | Version 12.0 |
| ZEN Blue | Zen | Version 3.3 |
| Other | ||
| Agilent 1260 Infinity LC system | Agilent Technologies | N/A |
| Agilent High Sensitivity D1000 Tapestation system | Agilent | N/A |
| Atlantis® HILIC column | Waters | N/A |
| Axio Scan.Z1 | Zeiss | N/A |
| Bioanalyzer | Agilent | N/A |
| C18 analytical column (1.9 μm) | Dr. Maisch GmbH | N/A |
| C18 HPLC column | Thermo Fisher Scientific | N/A |
| Cryotome FSE | Thermo Fisher Scientific | N/A |
| LabChip GX Touch | Revvity | N/A |
| NanoDrop | Thermo Fisher Scientific | N/A |
| Nikon C2plus confocal microscope | Nikon | N/A |
| NovaSeq 6000 | Illumina | N/A |
| Q-Exactive Fusion Lumos MS | Thermo Fisher Scientific | N/A |
| Q-Exactive HF-X MS | Thermo Fisher Scientific | N/A |
| QTRAP5500 Mass Spectrometer | AB Sciex | N/A |
| Savant SC210 SpeedVac | Thermo Fisher Scientific | N/A |
| Shiny App (Human-Heart-ALL) | The University of Sydney | http://shiny.maths.usyd.edu.au/Human-Heart-ALL/ |
| SpeedVac SPD120 | Thermo Fisher Scientific | N/A |
| ThermoMixerC | Eppendorf | N/A |
| TissueLyser LT | Qiagen | N/A |
| XBridge™ Amide column | Waters | N/A |